The aim of this study was to analyze the association between physical activity and eating habits during the COVID-19 pandemic among Brazilian adults. A sample of 1,929 participants answered an online survey, however 1,874 were included in the analysis. The impact of the COVID-19 pandemic on eating habits was assessed inquiring about participants' intake of fruits, vegetables, fried foods, and sweets during the pandemic. Physical activity was assessed by asking participants about their weekly frequency, intensity and number of minutes/hours engaging (...) in structured physical activities per week. Participants were then stratified into categories based on moderate-to-vigorous intensity and into active or inactive. Increased sweets consumption was the most commonly reported change to eating habits, followed by an increase in the consumption of vegetables, fruits, and fried foods. Physical activity practice was related to lower consumption of fried foods and sweets. A cluster analysis revealed subjects with higher the level of physical activity was more likely to follow a healthy diet. Thus, physical activity was positively associated with healthier eating habits. Health authorities must recommend regular physical as a strategy to improve overall health during the COVID-19 pandemic. Future studies should address the physical activity interventions to improve health status during a pandemic. (shrink)

BackgroundThe outbreak of novel coronavirus disease 2019 has caused a global panic and public concern due to its mortality ratio and lack of treatments/vaccines. Reduced levels of physical activity have been reported during the outbreak, affecting the normal daily pattern.ObjectiveTo investigate the relationship of physical activity level with sleep quality and the effects of reduction physical activity levels on sleep quality.MethodsA Google form was used to address personal information, COVID-19 personal care, physical activity, and mental health of 1,907 adult volunteers. (...) Binary logistic regression was used to verify the association of physical activity parameters and sleep quality.ResultsInsufficient physical activity levels were a risk factor to have disturbed sleep pattern [OR: 1.28, 95% CI ]; however, when the BMI was added to the analysis, there was no more statistical difference [OR: 1.23, 95% CI ]. On the other hand, we found that the reduction of physical activity levels was associated with negative changes in sleep quality [OR: 1.73, 95% CI ], regardless all the confounders [OR: 1.30, 95% CI ], unless when feeling of depression was added in Model 6 [OR: 1.28, 95% CI ].ConclusionDisruption in daily physical activity routine, rather than physical activity level, negatively influences sleep quality during the COVID-19 quarantine. (shrink)

We describe some of the ways that the field of content analysis is being transformed in an Era of Big Data. We argue that content analysis, from its beginning, has been concerned with extracting the main meanings of a text and mapping those meanings onto the space of a textual corpus. In contrast, we suggest that the emergence of new styles of text mining tools is creating an opportunity to develop a different kind of content analysis that we describe as (...) a computational hermeneutics. Here the goal is to go beyond a mapping of the main meaning of a text to mimic the kinds of questions and concerns that have traditionally been the focus of a hermeneutically grounded close reading, a reading that focuses on what Kenneth Burke described as the poetic meanings of a text. We illustrate this approach by referring to our own work concerning the rhetorical character of US National Security Strategy documents. (shrink)

In this anthology of new and classic articles, fifteen noted feminist philosophers explore contemporary ethical issues that uniquely affect the lives of women. These issues in applied ethics include autonomy, responsibility, sexual harassment, women in the military, new technologies for reproduction, surrogate motherhood, pornography, abortion, nonfeminist women and others. Whether generated by old social standards or intensified by recent technology, these dilemmas all pose persistent, 'nagging,' questions that cry out for answers.

Because visual narratives demand complex inference abilities, they can potentially be used as a tool for developing inferential skills in other domains, like reading. The Inferential Language Comprehension (iLC) Framework proposes an approach to using visual narratives in educational settings to sponsor inference skills by building on cognitive, developmental, and language research.

Ethics is the emphasis of our first-year Introduction to Clinical Medicine-1 course. Introduction to Clinical Medicine-1 uses problem-based learning to involve groups of seven to nine students and two facilitators in realistic clinical cases. The cases emphasize ethics, but also include human behaviour, basic science, clinical medicine, and prevention learning issues. Three cases use written vignettes, while the other three cases feature standardized patients. Groups meet twice for each case. In session one, students read the case introduction, obtain data from (...) the written case or standardized patient, identify the case's ethical problems, formulate learning issues, discuss ways to resolve the moral conflicts, and assign research responsibilities. In session two, students discuss their assigned learning issues and specify and justify clinical actions to address the case's ethical dilemmas. Following three cases, groups write an essay discussing what they learned and describing how they would approach and resolve the case's learning issues. (shrink)

Abstract In the last 20 years the ruthless competition for natural resources, political instability, armed conflicts, and the terrorist attacks of 9/11 have paved the way for private military and security companies (PMSCs) to operate in areas which were until recently the preserve of the state. PMSCs, less regulated than the toy industry, commit grave human rights violations with impunity. The United Nations has elaborated an international binding instrument to regulate their activities but the opposition of the U.S., U.K., and (...) other Western governments?and from PMSCs, which prefer self-regulation?have prevented any advancement. (shrink)

Over the past decades, anti-cancer treatments have evolved rapidly from cytotoxic chemotherapies to targeted therapies including oral targeted medications and injectable immunooncology and cell therapies. New anti-cancer medications come to markets at increasingly high prices, and health insurance coverage is crucial for patient access to these therapies. State laws are intended to facilitate insurance coverage of anti-cancer therapies.Using Massachusetts as a case study, we identified five current cancer coverage state laws and interviewed experts on their perceptions of the relevance of (...) the laws and how well they meet the current needs of cancer care given rapid changes in therapies. Interviewees emphasized that cancer therapies, as compared to many other therapeutic areas, are unique because insurance legislation targets their coverage. They identified the oral chemotherapy parity law as contributing to increasing treatment costs in commercial insurance. For commercial insurers, coverage mandates combined with the realities of new cancer medications — including high prices and often limited evidence of efficacy at approval — compound a difficult situation. Respondents recommended policy approaches to address this challenging coverage environment, including the implementation of closed formularies, the use of cost-effectiveness studies to guide coverage decisions, and the application of value-based pricing concepts. Given the evolution of cancer therapeutics, it may be time to evaluate the benefits and challenges of cancer coverage mandates. (shrink)

Biologists frequently draw on ideas and terminology from engineering. Evolutionary systems biology—with its circuits, switches, and signal processing—is no exception. In parallel with the frequent links drawn between biology and engineering, there is ongoing criticism against this cross-fertilization, using the argument that over-simplistic metaphors from engineering are likely to mislead us as engineering is fundamentally different from biology. In this article, we clarify and reconfigure the link between biology and engineering, presenting it in a more favorable light. We do so (...) by, first, arguing that critics operate with a narrow and incorrect notion of how engineering actually works, and of what the reliance on ideas from engineering entails. Second, we diagnose and diffuse one significant source of concern about appeals to engineering, namely that they are inherently and problematically metaphorical. We suggest that there is plenty of fertile ground left for a continued, healthy relationship between engineering and biology. (shrink)

Reumen. Se describen las bases del muestreo conglomerado y muestreo sistemático. Se presentan lasecuaciones pertinentes y aquellas para la estimación del tamaño óptimo de muestreo para cada tipo demuestreo. Se demuestra la aplicación práctica de éstos clases de muestreo por medio de ejemplosreales.Palabras claves. Muestreo conglomerado, muestreo sistemático, tamaño óptimo de la muestra.. Cluster sampling and systematic sampling are described and their equations are provided.Real examples are given in order to show the applications of these types of samplings. Equations toestimate (...) optimal sample sizes are also noted.Keywords. Cluster sampling, optimal sample size, systematic sampling. (shrink)

Die Kongressakten des 12. Internationalen Kant-Kongresses, der im Jahr des 650-Jahrjubiläums der Universität Wien zum Thema „Natur und Freiheit“ vom 21.–25. September 2015 an der Universität Wien stattgefunden hat, versammeln die Ergebnisse dieses Kongresses. Mit dem Thema „Natur und Freiheit“ wurde zwei tragenden Begriffen des Kritischen Werks Kants Rechnung getragen. Kants Philosophie wird bis heute weltweit diskutiert, was sich auch in den Teilnehmerinnen und Teilnehmern des Kongresses spiegelte. Gleichwohl wurden und werden immer wieder Zweifel an der Berechtigung einer Philosophie der (...) Freiheit laut, wie sie insbesondere für Kants Moralphilosophie grundlegend ist. Spannung und Balance von Natur und Freiheit galt es, erneut zu diskutieren. Überdies sollte am Ort des Kongresses, in Wien, der in der Vergangenheit brüchigen, von Vorbehalten bestimmten Auseinandersetzung mit Immanuel Kant in Österreich durch neue Untersuchungen Aufmerksamkeit geschenkt werden. Der Kongress hat die Bedeutung Kants für die heutige internationale Philosophie erneut unterstrichen. Es konnten aber auch die historischen Filiationen der Philosophie Kants für Wien und Österreich herausgearbeitet und einer neuen Sichtung unterzogen werden. (shrink)

Die Kongressakten des 12. Internationalen Kant-Kongresses, der im Jahr des 650-Jahrjubiläums der Universität Wien zum Thema „Natur und Freiheit“ vom 21.–25. September 2015 an der Universität Wien stattgefunden hat, versammeln die Ergebnisse dieses Kongresses. Mit dem Thema „Natur und Freiheit“ wurde zwei tragenden Begriffen des Kritischen Werks Kants Rechnung getragen. Kants Philosophie wird bis heute weltweit diskutiert, was sich auch in den Teilnehmerinnen und Teilnehmern des Kongresses spiegelte. Gleichwohl wurden und werden immer wieder Zweifel an der Berechtigung einer Philosophie der (...) Freiheit laut, wie sie insbesondere für Kants Moralphilosophie grundlegend ist. Spannung und Balance von Natur und Freiheit galt es, erneut zu diskutieren. Überdies sollte am Ort des Kongresses, in Wien, der in der Vergangenheit brüchigen, von Vorbehalten bestimmten Auseinandersetzung mit Immanuel Kant in Österreich durch neue Untersuchungen Aufmerksamkeit geschenkt werden. Der Kongress hat die Bedeutung Kants für die heutige internationale Philosophie erneut unterstrichen. Es konnten aber auch die historischen Filiationen der Philosophie Kants für Wien und Österreich herausgearbeitet und einer neuen Sichtung unterzogen werden. (shrink)

Quels rapports, depuis les commencements, les philosophes ontils noués avec la science? Il ne s'agit pas ici de dresser l'inventaire des problèmes philosophiques que soulèvent les sciences ou la science, ni d'évaluer les réponses qui y furent apportées, mais, à l'inverse, de s'interroger sur les manières multiples dont les philosophes se sont représenté la science - état d'un sujet connaissant ou activité savante - système d'énoncés ou méthode de recherche, voire ensemble de disciplines constituées - et les problèmes afférents à (...) chacune de ces représentations. A l'exhaustivité historique, il a été préféré le questionnement philosophique. L'ouvrage se déploie à partir de quatre grandes problématiques : " La science "? (Platon ; Descartes, Newton ; Leibniz ; L'Encyclopédie ; Carnap) ; Critiques et limites de la science (empirisme et scepticisme anglais ; Kant ; Bergson, Brunschvicg ; Heidegger ; Wittgenstein) ; Science et naturalisme (Aristote ; Mach ; Bolzano ; Husserl ; Quine) Science, histoire et société (Comte ; Durkheim ; l'école de Francfort ; Bachelard, Canguilhem, Foucault ; logique de la science et révolutions scientifiques). (shrink)

Lateral temporal measures of the auditory evoked potential including the T-complex, as well as an earlier negative peak index maturation of auditory/speech processing. Previous studies have shown that these measures distinguish neural processing in children with typical language development from those with disorders and monolingual from bilingual children. In this study, bilingual children with Turkish as L1 and German as L2 were compared with monolingual German-speaking children with developmental language disorder and monolingual German-speaking children with TD in order to disentangle (...) effects of limited language input vs. reduced perceptual abilities in the processing of speech and non-speech stimuli. Sensory processing reflected by the T-complex was compared in response to a German vowel and a sine-wave tone in the three groups of children, ages 5 through 6 years. Stimuli were presented while children watched a muted video. Auditory evoked potentials were time-locked to the vowels and tones. AEPs to the frequent stimuli within an oddball paradigm were analyzed at the left and right temporal electrode sites.The results revealed language status, stimulus, and language test measures all influenced the T-complex amplitudes. Particularly, the peak amplitude of Ta was modulated by language status and stimulus type. Bilingual children had significantly more negative Ta responses than the monolingual children with TD for both vowels and tones while DLD children differed from TD children only for the vowel stimulus. The amplitude of the T-complex was overall more negative at the left than at the right site. The Na peak latency was longer for the bilingual group than that observed for the two monolingual groups. The Tb latency was shorter for DLD and bilingual groups than that for TD children in the vowel condition, but no such latency difference between DLD and bilingual children was found. We suggest that the attenuated T-complex for bilingual children indicates continued plasticity of the auditory cortex to allow for learning of novel, second-language speech sounds. (shrink)

The high prevalence of cardiovascular diseases demands a reliable and sensitive risk assessment technique. In order to develop a fast and label-free immunosensor for C-reactive protein, a risk factor for this condition, anti-CRP antibodies were physically adsorbed to the hydrogen -terminated surface of nanocrystalline diamond. An Enzyme-Linked ImmunoSorbent Assay reference technique showed that this was a suitable substrate for antibody-antigen recognition reactions. Electrochemical Impedance Spectroscopy was used to electronically detect CRP recognition. The specificity of the immunosensor was demonstrated by incubation (...) with CRP and plasminogen as reference molecule. A different impedance behavior was observed in real-time after CRP addition as compared to plasminogen addition: the impedance increased only during CRP incubation. Fitting the data showed that this corresponded with a decrease in capacitance of the molecular layer due to its increased thickness by specific CRP recognition. Sensitivity experiments in real-time showed a clear discrimination between 1 μM, 100 nM, and 10 nM of CRP after 10 min at 100 Hz. Since, 10 nM of CRP was still clearly distinguishable from buffer solution, our CRP-directed immunosensor prototype reaches a sensitivity that is within the physiologically relevant concentration range of this biomarker in healthy controls and CVD patients. Moreover, this prototype displayed real-time discriminating power between spiked and unspiked serum, and thus also shows its applicability in this biological matrix. © 2011 Elsevier B.V. All rights reserved. (shrink)

Dans cet article, j’essaie de montrer que l’idée du langage comme calcul structure la philosophie de Wittgenstein dans le Big Typescript. Pour ce faire, je commence par mettre en relief les différences entre la conception du langage comme calcul dans le Tractatus, et sa reformulation dans le Big Typescript ; j’explique ensuite comment l’idée de l’autonomie de la grammaire est à la base de la conception de la « grammaire » ou du langage comme calcul. J’espère pouvoir montrer ainsi l’unité (...) de la philosophie de Wittgenstein aux alentours de 1932-1933. Il doit en ressortir que sa philosophie à l’époque du Big Typescript présente un intérêt en elle-même, quoiqu’il ne s’agisse pas encore de la philosophie des Recherches philosophiques.I aim at showing that the idea of language as a calculus is the central view that shapes Wittgenstein’s philosophy in the Big Typescript. In order to do so, I first contrast the conception of language as a calculus in the Tractatus with its reformulation in the BigTypescript ; then I explain how the idea of the autonomy of grammar grounds the conception of “grammar” or language as calculus. With this on hand, I give an overview of the unity of Wittgenstein’s philosophy around 1932-1933. It should become clear that his philosophy at the time is worth arguing for, even though it is not yet the philosophy of the PhilosophicalInvestigations. (shrink)

After the works of Jaako Hintikka, David Stern and, more recently, Denis Perrin, the idea that there is a wittgensteinian reflection upon the time and that it is at the origin of the abandonment of the project of a phenomenological language is nothing surprising, but we cannot consider it established yet. It seems to me that an important element in this debate is in chapter VII of the Philosophical Remarks : indeed, we find there the very first sustained discussion on (...) the possibility of a phenomenological language —a discussion obviously centred on the question of time. Without aiming to propose an “alternative” reading of Wittgenstein’ reflections on time and the phenomenological language, I would like to bring to light the importance of this chapter for this problem and also try to show that the interpretation key must be looked for in a reductio ad absurdum whose base is the impossibility to measure time. (shrink)

Les Remarques philosophiques sont la première tentative de mettre en oeuvre le programme qui découle de l’échec du projet du Tractatus Logico-Philosophicus. Le noyau de ce programme est donné par l’abandon de l’analyse des nombres avancée dans le Tractatus. Wittgenstein se rend compte que les nombres doivent se trouver à la base même du langage, dans la structure des propositions élémentaires. En même temps, il se rend compte qu’il est impossible de fournir la logique sousjacente au langage avant d’avoir procédé (...) à l’analyse. Le projet d’une investigation logique des phénomènes s’imposait, donc, même après l’abandon de l’idée d’un langage phénoménologique. The Philosophical Remarks is a first attempt at pursuing the philosophical agenda determined by the failure of the Tractarian project. The central point of this agenda is the abandonment of the analysis of number that had been given in the Tractatus. Wittgenstein realizes that numbers should be brought back to the basis of language, as part of the structure of the elementary propositions themselves. At the same time, he realizes that it is impossible to give the logic underlying our language before the process of logical analysis is carried out. He undertakes the project of a logical investigation of phenomena even after giving up the idea of a phenomenological language. (shrink)

Les Remarques philosophiques sont la première tentative de mettre en oeuvre le programme qui découle de l’échec du projet du Tractatus Logico-Philosophicus. Le noyau de ce programme est donné par l’abandon de l’analyse des nombres avancée dans le Tractatus. Wittgenstein se rend compte que les nombres doivent se trouver à la base même du langage, dans la structure des propositions élémentaires. En même temps, il se rend compte qu’il est impossible de fournir la logique sousjacente au langage avant d’avoir procédé (...) à l’analyse. Le projet d’une investigation logique des phénomènes s’imposait, donc, même après l’abandon de l’idée d’un langage phénoménologique. The Philosophical Remarks is a first attempt at pursuing the philosophical agenda determined by the failure of the Tractarian project. The central point of this agenda is the abandonment of the analysis of number that had been given in the Tractatus. Wittgenstein realizes that numbers should be brought back to the basis of language, as part of the structure of the elementary propositions themselves. At the same time, he realizes that it is impossible to give the logic underlying our language before the process of logical analysis is carried out. He undertakes the project of a logical investigation of phenomena even after giving up the idea of a phenomenological language. (shrink)

After the works of Jaako Hintikka, David Stern and, more recently, Denis Perrin, the idea that there is a wittgensteinian reflection upon the time and that it is at the origin of the abandonment of the project of a phenomenological language is nothing surprising, but we cannot consider it established yet. It seems to me that an important element in this debate is in chapter VII of the Philosophical Remarks : indeed, we find there the very first sustained discussion on (...) the possibility of a phenomenological language —a discussion obviously centred on the question of time. Without aiming to propose an “alternative” reading of Wittgenstein’ reflections on time and the phenomenological language, I would like to bring to light the importance of this chapter for this problem and also try to show that the interpretation key must be looked for in a reductio ad absurdum whose base is the impossibility to measure time. (shrink)

Europe as a political entity is born with the general public disagreement against the Iraqi war, while governments were divided on that point. Those linked with European opinion are going to build politics together while the others will remain in a corm on market. This new political stage is supported by the global movement.

L’idée d’organiser à Paris un congrès international de philosophie scientifique « fut émise pour la première fois au cours d’une conversation à Berlin, en juillet 1932, entre Hans Reichenbach et Louis Rougier ». Dans une lettre du 6 août 1932 adressée à Reichenbach, Rougier mentionne déjà des contacts avec le ministère des Affaires étrangères pour obtenir des subventions et le 6 novembre de la même année, il propose à Reichenbach de tenir la manifestation en 1934 [voir Padovani 2006, 239-–240...

HALLETT C and WAGNER L. Nursing Inquiry 2011; 18: 359–368 Promoting the health of Europeans in a rapidly changing world: a historical study of the implementation of World Health Organisation policies by the Nursing and Midwifery Unit, European Regional Office, 1970–2003The World Health Organisation (WHO) was inaugurated in 1948. Formed in a period of post‐war devastation, WHO aimed to develop and meet goals that would rebuild the health of shattered populations. The historical study reported here examined the work of (...) the Nursing and Midwifery Unit (NMU) of WHO’s European Regional Office during the later part of the twentieth century. The study examined archive sources lodged at the NMU archive. The sources included manuscripts relating to important NMU initiatives, reports and papers published by WHO, and a range of secondary sources. The study identified three main driving forces in the work of the NMU of the European Regional Office of WHO. One of the strongest of these was a drive to develop and promote the nursing profession within the countries of the European Region. The second was the promulgation and implementation of the positive public health strategies of WHO, particularly its ‘38 Targets for Health for All by the Year 2000’. The third focussed on securing equity across the European continent and on promoting the development of the nursing professions in poorer and less‐developed countries. The study concludes that the nursing professions in European states grew in strength and influence, and that the health of populations improved throughout the continent between 1970 and 2003. It discusses the extent to which the role of the NMU in these advances may have been significant. (shrink)